Which nursing diagnosis should receive the highest priority when caring for a patient receiving total parenteral nutrition?

• A. Infection, Risk for
• B. Trauma, Risk for
• C. Skin Integrity, Impaired
• D. Fluid Volume, Risk for Imbalance

Answer: (A)

Total parenteral nutrition relies on a central venous catheter, which is a direct entry point for microbes. The biggest danger in this scenario is a catheter‑related infection that can quickly progress to sepsis and threaten organ function. Therefore, preventing infection takes priority over other potential concerns, even though issues like skin integrity, fluid balance, or trauma are important to monitor. In practice, this means meticulous aseptic technique, careful line and dressing care, and prompt attention to any signs of infection to protect the patient’s stability.